Is Psychedelic Therapy Legal in Colombia?

Isolated psilocybin/psilocin scheduled (Art. 376) with no therapeutic/prescription pathway (trial-only via INVIMA). Whole mushrooms, spores and grow kits not specifically controlled, and personal dose decriminalized (Constitutional Court C-221/1994). No lawful supply or therapy.

Scheduled/prohibited (UN-listed, Art. 376). No medical/prescription pathway; clinical-trial-only via INVIMA. Personal-dose possession decriminalized in principle (C-221/1994) but supply/therapeutic use prohibited.

No specific national legislation; absence of a schedule entry plus C-221/1994 creates a documented gray area, and Medellin-area retreats operate informally with no safety regulation or formal pathway.

DMT scheduled, but the yage brew (Banisteriopsis caapi + Psychotria viridis) is not controlled and widely consumed. Strong constitutional protection for Indigenous/traditional ceremonial use under recognized taitas (Law 21/1991, ILO 169) — a cultural exemption, not general legalization; non-Indigenous retreats tolerated as a gray area with no therapeutic pathway.

Isolated mescaline UN Schedule I, prohibited (Art. 376); no therapeutic pathway. San Pedro (Trichocereus, native) not itself scheduled — live plant generally not prosecuted, but consumable preparations fall under the mescaline prohibition; peyote not native. Personal dose under C-221/1994.

Tracked separately — a prescription medicine, excluded from the blended status.

Prescription anesthetic regulated by INVIMA as a controlled medicinal product; lawful via prescription/hospital use.