Is Psychedelic Therapy Legal in Missouri?
Classic psychedelics are prohibited under Missouri state law, with no state-regulated therapeutic pathway.
Status by substance
State-level status for lawful supervised therapeutic use. Regardless of state law, classic psychedelics remain Schedule I federally. Last reviewed 2026-06.
Psilocybin
IllegalSchedule I; no decrim. HB 1830 right-to-try psilocybin/MDMA for terminal patients/veterans pending — not enacted; no general therapeutic access.
Official source (2026-02) ↗MDMA
IllegalSchedule I; only pending right-to-try legislation, not enacted.
Official source (2026-02) ↗Mescaline / Peyote
IllegalPeyote/mescaline Schedule I; federal NAC religious exemption only.
Official source (2026-01) ↗Ketamine
Legal / regulated accessTracked separately — a prescription medicine, excluded from the blended status.
Prescription / off-label therapeutic use (FDA-approved anesthetic; Spravato).
Official source (2019-03) ↗Educational information, not legal advice. Laws change — confirm with the official sources above before making decisions.
Looking for legal psychedelic-assisted therapy?
ATMA CENA provides supervised, legal psychedelic-assisted therapy in Canada and trains practitioners across North America.