Is Psychedelic Therapy Legal in South Carolina?
Classic psychedelics are prohibited under South Carolina state law, with no state-regulated therapeutic pathway.
Status by substance
State-level status for lawful supervised therapeutic use. Regardless of state law, classic psychedelics remain Schedule I federally. Last reviewed 2026-06.
Psilocybin
IllegalSchedule I; no therapeutic access, decriminalization, or municipal resolutions.
Official source (2026-06) ↗Mescaline / Peyote
IllegalMescaline Schedule I; peyote only via federal NAC exemption.
Official source (2026-06) ↗Ketamine
Legal / regulated accessTracked separately — a prescription medicine, excluded from the blended status.
Prescription / off-label therapeutic use.
Official source (2026-06) ↗Educational information, not legal advice. Laws change — confirm with the official sources above before making decisions.
Looking for legal psychedelic-assisted therapy?
ATMA CENA provides supervised, legal psychedelic-assisted therapy in Canada and trains practitioners across North America.